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11 p, 265.1 KB |
Safinamide in clinical practice : A Spanish multicenter cohort study
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Martí-Andrés, Gloria (Clínica Universidad de Navarra) ;
Jiménez-Bolaños, Rayco (Hospital Universitario Insular de Gran Canaria) ;
Arbelo, José Matías (Hospital Universitario Insular de Gran Canaria) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Duran-Herrera, Carmen (Hospital Universitario de Badajoz) ;
Valenti-Azcarate, Rafael (Clínica Universidad de Navarra) ;
Luquin, Maria-Rosario (Clínica Universidad de Navarra) ;
Universitat Autònoma de Barcelona
Safinamide is an approved drug for the treatment of motor fluctuations of Parkinson's Disease (PD) patients with a potential benefit on non-motor symptoms (NMS). A retrospective multicenter cohort study was conducted, in which the clinical effect of safinamide on both motor and NMS was assessed by the Clinical Global Impression of Change scale. [...]
2019 -  10.3390/brainsci9100272
Brain sciences, Vol. 9 Núm. 10 (october 2019) , p. 272
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4 p, 231.1 KB |
Gender Perspective in Dual Diagnosis
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Torrens, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Orengo, Teresa (Hospital Clínic València) ;
Rodríguez de Fonseca, Fernando (Instituto de Investigaciones Biomédicas de Málaga) ;
Almodóvar, Isabel (Universidad CEU Cardenal Herrera) ;
Baquero, Abel (Universidad CEU Cardenal Herrera) ;
Benito, Ana (Universidad CEU Cardenal Herrera) ;
Universitat Autònoma de Barcelona
Little data are available for women diagnosed with a dual diagnosis. However, dual diagnosis in women presents increased stigma, social penalties, and barriers to access to treatment than it does for men. [...]
2021 - 10.3390/brainsci11081101
Brain sciences, Vol. 11 (august 2021)
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15 p, 1.9 MB |
Can the Addition of Maintenance Electroconvulsive Therapy to Pharmacotherapy Improve Relapse Prevention in Severe Major Depressive Disorder? A Randomized Controlled Trial
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Martínez-Amorós, Erika (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cardoner, N. (Narcís) (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Gálvez, Verònica (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
De Arriba-Arnau, Aida (Hospital Universitari de Bellvitge) ;
Soria, Virginia (Hospital Universitari de Bellvitge) ;
Palao, Diego Jose (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Menchón, José M. (Hospital Universitari de Bellvitge) ;
Urretavizcaya, Mikel (Hospital Universitari de Bellvitge)
Few systematic evaluations have been performed of the efficacy of electroconvulsive therapy (ECT) as a relapse prevention strategy in major depressive disorder (MDD). This is a single-blind, multicenter, randomized controlled trial to compare the efficacy and tolerability of pharmacotherapy plus maintenance ECT (M-Pharm/ECT) versus pharmacotherapy alone (M-Pharm) in the prevention of MDD relapse. [...]
2021 - 10.3390/brainsci11101340
Brain sciences, Vol. 11 (october 2021)
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13 p, 1.1 MB |
Developing a Digital Solution for Remote Assessment in Multiple Sclerosis : From Concept to Software as a Medical Device
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van der Walt, Anneke (The Alfred, Melbourne) ;
Butzkueven, Helmut (Monash University) ;
Shin, Robert K. (MedStar Georgetown University Hospital) ;
Midaglia, Luciana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Capezzuto, Luca (F. Hoffmann-La Roche Ltd) ;
Lindemann, Michael (F. Hoffmann-La Roche Ltd) ;
Davies, Geraint (F. Hoffmann-La Roche Ltd) ;
Butler, Lesley M. (F. Hoffmann-La Roche Ltd) ;
Costantino, Cristina (F. Hoffmann-La Roche Ltd) ;
Montalban, Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
There is increasing interest in the development and deployment of digital solutions to improve patient care and facilitate monitoring in medical practice, e. g. , by remote observation of disease symptoms in the patients' home environment. [...]
2021 - 10.3390/brainsci11091247
Brain sciences, Vol. 11 (september 2021)
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16 p, 366.6 KB |
Depression in Major Neurodegenerative Diseases and Strokes : A Critical Review of Similarities and Differences among Neurological Disorders
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Pagonabarraga Mora, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Álamo, Cecilio (Universidad de Alcalá) ;
Castellanos, María del Mar (Instituto de Investigación Biomédica de A Coruña) ;
Díaz, Samuel (Hospital Universitari i Politècnic La Fe (València)) ;
Manzano, Sagrario (Hospital Universitario Infanta Leonor)
Depression and anxiety are highly prevalent in most neurological disorders and can have a major impact on the patient's disability and quality of life. However, mostly due to the heterogeneity of symptoms and the complexity of the underlying comorbidities, depression can be difficult to diagnose, resulting in limited recognition and in undertreatment. [...]
2023 - 10.3390/brainsci13020318
Brain sciences, Vol. 13 (february 2023)
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18 p, 1.9 MB |
Present and future of parkinson's disease in Spain : Parkinson-2030 delphi project
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Santos García, Diego (Department of Neurology. CHUAC (Complexo Universitario de A Coruña)) ;
Blázquez Estrada, Marta (Hospital Universitario Central de Asturias) ;
Calopa, Matilde (Hospital Universitari de Bellvitge) ;
Escamilla Sevilla, Francisco (Instituto de Investigación Sanitaria de Granada) ;
Freire, Eric (Departamento de Neurología. Hospital IMED Elche) ;
García Ruiz, Pedro J. (Servicio de Neurología. Fundación Jiménez Díaz) ;
Grandas, Francisco (Hospital General Universitario Gregorio Marañón) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
López Manzanares, Lydia (Hospital Universitario de la Princesa (Madrid)) ;
Martínez-Castrillo, Juan Carlos (Hospital Universitario Ramón y Cajal (Madrid)) ;
Mir, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Pérez-Errazquin, Francisco (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Salom, José María (Hospital Clínic Universitari (València)) ;
Tijero, Beatriz (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Valldeoriola, Francesc (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Yáñez, Rosa (Servicio de Neurología. Complejo Hospitalario Univ. Ourense) ;
Avilés, Arantxa (Departamento Médico. Zambon S.A.U) ;
Luquin, Maria-Rosario (Instituto de Investigación Sanitaria de Navarra) ;
Universitat Autònoma de Barcelona
Parkinson's disease (PD) is a chronic progressive and irreversible disease and the second most common neurodegenerative disease worldwide. In Spain, it affects around 120. 000-150. 000 individuals, and its prevalence is estimated to increase in the future. [...]
2021 - 10.3390/brainsci11081027
Brain sciences, Vol. 11 Núm. 8 (august 2021) , p. 1027
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11 p, 431.4 KB |
Validation and Normative Data on the Verbal Fluency Test in a Peruvian Population Ranging from Pediatric to Elderly Individuals
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Zegarra Valdivia, Jonathan Adrián (Faculty of Health Sciences. Universidad Señor de Sipán) ;
Chino, Brenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Paredes Manrique, Carmen Noelia (Psychology Department. Universidad Nacional de San Agustín de Arequipa)
In neuropsychological evaluation, verbal fluency is a crucial measure of cognitive function, but this measure requires standardized and normative data for use. The present study aimed to obtain validation and normative data for the verbal fluency task in the Peruvian population, with participants ranging from 6 to 94 years and varying in age, educational level, and sex. [...]
2022 - 10.3390/brainsci12121613
Brain sciences, Vol. 12 Núm. 12 (december 2022) , p. 1613
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16 p, 338.0 KB |
Childhood Maltreatment and Its Interaction with Hypothalamic-Pituitary-Adrenal Axis Activity and the Remission Status of Major Depression : Effects on Functionality and Quality of Life
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Salvat-Pujol, Neus (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Labad, Javier (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Urretavizcaya, Mikel (Universitat de Barcelona. Departament de Ciències Clíniques) ;
De Arriba-Arnau, Aida (Centro de Investigación Biomédica en Red de Salud Mental) ;
Segalàs, Cinto (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Real, Eva (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Ferrer, Alex (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Crespo, José Manuel (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Jiménez-Murcia, Susana (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Menchón Magriñá, José Manuel (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Soria, Virginia (Universitat de Barcelona. Departament de Ciències Clíniques)
Relationships among childhood maltreatment (CM), hypothalamic-pituitary-adrenal (HPA) axis disturbances, major depressive disorder (MDD), poor functionality, and lower quality of life (QoL) in adulthood have been described. [...]
2021 - 10.3390/brainsci11040495
Brain sciences, Vol. 11 (april 2021)
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13 p, 966.2 KB |
Observing pain in individuals with cognitive impairment : A pilot comparison attempt across countries and across different types of cognitive impairment
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Kunz, M. (University of Augsburg. Department of Psychology and Sociology) ;
Crutzen-Braaksma, P. (University of Groningen. Department of General Practice and Elderly Care Medicine) ;
Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Invitto, S. (University of Salento. Department of Biological and Environmental Sciences and Technologies) ;
Villani, G. (University of Salento. Department of Biological and Environmental Sciences and Technologies) ;
Detommaso, M. (Bari Aldo Moro University. Applied Neurophysiology and Pain Unit) ;
Petrini, L. (Aalborg University. Department of Health Science and Technology) ;
Vase, L. (Aarhus University. Department of Psychology and Behavioral Sciences) ;
Matthiesen, S. T. (Aarhus University. Department of Psychology and Behavioral Sciences) ;
Gottrup, H. (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Echeita, J. A. (University of Groningen. Department of Rehabilitation Medicine) ;
Lautenbacher, S. (University of Bamberg. Department of Physiological Psychology) ;
Defrin, R. (Tel Aviv University. Department of Physical Therapy) ;
Universitat Autònoma de Barcelona.
Departament de Psiquiatria i de Medicina Legal
Facial expression is a key aspect in observational scales developed to improve pain assessment in individuals with cognitive impairments. Although these scales are used internationally in individuals with different types of cognitive impairments, it is not known whether observing facial expressions of pain might differ between regions or between different types of cognitive impairments. [...]
2021 - 10.3390/brainsci11111455
Brain sciences, Vol. 11 Núm. 11 (november 2021) , p. 1455
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